Ethanol → HCID 178527825, compound

HRID 1354340Notes

Reaction equation

HRID 1354340 reaction equation
[C:1]1([C:7]([CH:9]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)O)=O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:17][C:18]([NH2:20])=[S:19].C(O)C>CN(C)C=O>[C:1]1([C:7]2[N:17]=[C:18]([SH:19])[NH:20][C:9]=2[C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

5

Reactant 3

HCID 702EthanolHCID 8400BenzoinHCID 2723790Thiourea

Product 1

HCID 178527825HCID 178527825, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent2×

Procedure

21.2 g (0.10 mol) of benzoin were dissolved in DMF (dimethylformamide) with 10.8 g (0.15 mol) of thiourea with warming and the mixture was heated under reflux for 15 hours. After cooling, the DMF was stripped off and the residue was treated with ethanol. The precipitate resulting in the course of this was filtered off with suction, washed with cold ethanol, dried and reused without further purification. The yield was 18.4 g.

Workup

  1. temperaturewith warming
  2. temperaturethe mixture was heated
  3. temperatureunder reflux for 15 hours
  4. temperatureAfter cooling
  5. customThe precipitate resulting in the course of
  6. filtrationthis was filtered off with suction
  7. washwashed with cold ethanol
  8. customdried
  9. customreused without further purification

Sources & evidence

ORD record
ord-10bcc0b892b24be1bf57769097e21a0a
Source dataset
uspto-grants-2007_05
Patent number
US07223781B2

Reaction notes

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