HCID 86598976, compound → 2-[(2,5-Dichlorophenyl)thio]-2-phenylethylamine hydrochloride

HRID 1354396Notes

Reaction equation

HRID 1354396 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([Cl:8])=[CH:4][C:3]=1[S:9][CH:10]([C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)[CH2:11][NH:12]C(=O)OC(C)(C)C>Cl.O1CCOCC1>[ClH:1].[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([Cl:8])=[CH:4][C:3]=1[S:9][CH:10]([C:20]1[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=1)[CH2:11][NH2:12]

Participants

4

Reactant 1

HCID 86598976HCID 86598976, compound

Product 1

HCID 211058002-[(2,5-Dichlorophenyl)thio]-2-phenylethylamine hydrochlorideYield 142.8%

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidSolventHCID 312751,4-DioxaneSolvent

Procedure

The product from step (b) (0.4 g) was dissolved in 4M HCl in dioxane (5 ml). The resulting solution was stirred at room temperature for 6 h, the solvent was evaporated and the residue triturated with ethyl acetate to give of the title compound (0.24 g) as, a white solid.

Workup

  1. customthe solvent was evaporated
  2. customthe residue triturated with ethyl acetate

Sources & evidence

ORD record
ord-068525873f0548958249a87c4e0f4ad0
Source dataset
uspto-grants-2007_05
Patent number
US07223794B2

Reaction notes

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