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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1354398Generated: November 2, 2026

Oxalic Acid → HCID 178510127, compound

https://huagongshe.com/reaction/1354398

Reaction equation

Participants

RoleNameHCIDCharge
ReactantOxalic AcidHCID 971—
ReactantEthyl 2-hydroxyacetimidate hydrochlorideHCID 12383662—
Reactant2-[[(1S)-2-Amino-1-phenylethyl]oxy]-4-chloro-5-fluorobenzonitrile (E)-butenedioateHCID 131726460—
ProductHCID 178510127HCID 178510127—

Reaction Steps

The title compound was prepared by the method of Example 5 using ethyl 2-hydroxyethanimidate hydrochloride in metianol and the ethanedioic acid salt of the product from Example 1 step (c). M.p. 196° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07223794B2
Source datasetuspto-grants-2007_05
ORD IDord-48239bd7ecd147b8a7a5d020c6e134f9
Source noteuspto-grants-2007_05