HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1'-Carbonyldiimidazole → N-Methyl-N-[1-(4-{3-[4-(pyridin-3-yloxy)phenyl]ureido}phenyl)pyrrolidin-3-yl]acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | 4-(Pyridin-3-Yloxy)Aniline | HCID 3159631 | — |
| Reactant | N-[1-(4-aminophenyl)pyrrolidin-3-yl]-N-methylacetamide | HCID 21105566 | — |
| Product | N-Methyl-N-[1-(4-{3-[4-(pyridin-3-yloxy)phenyl]ureido}phenyl)pyrrolidin-3-yl]acetamide | HCID 21105626 | — |
Reaction Steps
N-[1-(4-Aminophenyl)pyrrolidin-3-yl]-N-methylacetamide was reacted with carbonyldiimidazole and then with 4-(pyridin-3-yloxy)phenylamine by method A. This resulted in the product with the molecular weight of 445.53 (C25H27N5O3); MS (ESI): 446 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07223788B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-40516598f36e4bb083667aad9adb9763 |
| Source note | uspto-grants-2007_05 |