HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chloronicotinic acid → 6-chloro-N-[4-(3-dimethylaminopyrrolidin-1-yl)phenyl]nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chloronicotinic acid | HCID 79222 | — |
| Reactant | 1-(4-aminophenyl)-N,N-dimethylpyrrolidin-3-amine | HCID 21916591 | — |
| Product | 6-chloro-N-[4-(3-dimethylaminopyrrolidin-1-yl)phenyl]nicotinamide | HCID 21105534 | — |
Reaction Steps
6-Chloronicotinic acid was reacted with [1-(4-amino-phenyl)pyrrolidin-3-yl]dimethylamine by method E-b. This resulted in the product with the molecular weight of 344.14 (C18H21ClN4O); MS (ESI): 345 (M+H+) as hydrotrifluoroacetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07223788B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-005d22e24df44083bbe017e57d3bc100 |
| Source note | uspto-grants-2007_05 |