Isobutyryl chloride → HCID 58866843, compound

HRID 1354749Notes

Reaction equation

[CH3:1][N:2]([CH3:30])[CH:3]1[CH2:7][CH2:6][N:5]([C:8]2[CH:13]=[CH:12][C:11]([NH:14][C:15]([C:17]3[O:18][C:19]([C:22]4[CH:27]=[CH:26][C:25]([CH3:28])=[CH:24][C:23]=4[NH2:29])=[CH:20][CH:21]=3)=[O:16])=[CH:10][CH:9]=2)[CH2:4]1.[C:31](Cl)(=[O:35])[CH:32]([CH3:34])[CH3:33]>>[CH3:30][N:2]([CH3:1])[CH:3]1[CH2:7][CH2:6][N:5]([C:8]2[CH:13]=[CH:12][C:11]([NH:14][C:15]([C:17]3[O:18][C:19]([C:22]4[CH:27]=[CH:26][C:25]([CH3:28])=[CH:24][C:23]=4[NH:29][C:31](=[O:35])[CH:32]([CH3:34])[CH3:33])=[CH:20][CH:21]=3)=[O:16])=[CH:10][CH:9]=2)[CH2:4]1

Participants

Reactant 2

HCID 62325Isobutyryl chloride

HCID 58867390HCID 58867390, compound

Product 1

HCID 58866843HCID 58866843, compound

Procedure

5-(2-Amino-4-methylphenyl)furan-2-carboxylic acid [4-(3-dimethylamino-pyrrolidin-1-yl)-phenyl]amide was reacted with isobutyryl chloride by method Q. This resulted in the product with the molecular weight of 474.26 (C28H34N4O3); MS (ESI): 475 (M+H+).

Workup

customThis resulted in the product with the molecular weight of 474.26 (C28H34N4O3)

Sources & evidence

ORD record: ord-9e00d8f9a563451e99a20ebd77d5e713
Source dataset: uspto-grants-2007_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07223788B2

Reaction notes

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