Dopamine → Dopamine

HRID 1355319Notes

Reaction equation

HRID 1355319 reaction equation
[NH2:1][CH2:2][CH2:3][C:4]1[CH:11]=[CH:10][C:8]([OH:9])=[C:6]([OH:7])[CH:5]=1.[O:12]=[C:13]([C@H:15]([CH2:17][C:18]1[CH:25]=[C:23](O)[C:21](O)=[CH:20][CH:19]=1)[NH2:16])[OH:14]>>[NH2:16][C@H:15]([C:13]([OH:14])=[O:12])[CH2:17][C:18]1[CH:25]=[CH:23][CH:21]=[CH:20][CH:19]=1.[NH2:1][CH2:2][CH2:3][C:4]1[CH:11]=[CH:10][C:8]([OH:9])=[C:6]([OH:7])[CH:5]=1

Participants

4

Reactant 2

HCID 681Dopamine2×HCID 6047Levodopa

Product 2

HCID 681DopamineHCID 6140L-Phenylalanine

Procedure

The formation of trinitrophenyl-1-dopamine from dopamine (and hence the formation of dopamine from dopa) was measured in a spectrophotometer using ε340 nm=12,400 M−1 cm−1. In this assay, Phe-DC formed 9.4 nmol of dopamine and Di-ADC formed 2.74 nmol of dopamine, demonstrating once again that Di-ADC is an aromatic amino acid decarboxylase.

Sources & evidence

ORD record
ord-d186d3bfad114737971cb7092f27d2f3
Source dataset
uspto-grants-2003_07
Patent number
US06586173B2

Reaction notes

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