4-(Chloromethyl)-5-methyl-1-trityl-1H-imidazole → 4-[7-Methyl-3,3-bis-(5-methyl-1-trityl-1h-imidazol-4-ylmethyl)-1-naphthalen-1-ylmethyl-2-oxo-2,3-dihydro-1h-indol-6-yl]-benzonitrile

Participants

Reaction Steps

Following the same procedure as described in example 14A, the reaction of the title compound of 13A (0.191 g, 0.49 mmol) and 4-chloromethyl-5-methyl-1-trityl-1H-imidazole (0.55 g, 1.48 mmol) yielded the title compound of 15A (282.2 mg, 71% yield).

Provenance & Evidence