Dimethylformamide dimethyl acetal → HCID 18507644, compound

HRID 1355706Notes

Reaction equation

HRID 1355706 reaction equation
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]([CH2:8][C:9]#[N:10])=O.COC(OC)[N:14]([CH3:16])C.C(=O)(O)O.[NH2:23][C:24](N)=[NH:25].C[O-].[Na+]>CO>[NH2:25][C:24]1[N:23]=[C:6]([C:2]2[O:1][CH:5]=[CH:4][CH:3]=2)[C:8]([C:16]#[N:14])=[CH:9][N:10]=1

Participants

6

Reactant 4

HCID 78373Dimethylformamide dimethyl acetalHCID 1416712-FuroylacetonitrileHCID 286947Carbonic acid-guanidine (1:1)HCID 10942334Sodium Methoxide

Product 1

HCID 18507644HCID 18507644, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

From 2-furoylacetonitrile and N,N-dimethylformamide dimethyl acetal. Then treatment with guanidine carbonate and sodium methylate in methanol. EI-MS m/e (%): 186 (M+, 100).

Sources & evidence

ORD record
ord-4b96cabc2c3f4b4b95701a4a9c6aceaf
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

Loading…