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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1355716Generated: November 1, 2026

Benzyl Bromide → 2-Amino-4-benzylsulfanyl-6-phenyl-pyrimidine-5-carbonitrile

https://huagongshe.com/reaction/1355716

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl BromideHCID 7498—
ReactantSodium ethoxideHCID 2723922—
ReactantHCID 178509378HCID 178509378—
SolventEthanolHCID 702—
Product2-Amino-4-benzylsulfanyl-6-phenyl-pyrimidine-5-carbonitrileHCID 18507568—

Reaction Steps

From 2-amino-4-phenyl-6-thioxo-1,6-dihydro-pyrimidine-5-carbonitrile, benzyl bromide and sodium ethylate in ethanol. EI-MS m/e (%):318 (M+, 50), 317 ([M—H]+, 100), 285 (20), 91 (84).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06586441B2
Source datasetuspto-grants-2003_07
ORD IDord-59c9a145e7fa4e97a23af9025db4a083
Source noteuspto-grants-2003_07