Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1355720Generated: November 1, 2026

Bromocyclopentane → 2-Amino-4-cyclopentylsulfanyl-6-phenyl-pyrimidine-5-carbonitrile

https://huagongshe.com/reaction/1355720

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBromocyclopentaneHCID 8728—
ReactantSodium ethoxideHCID 2723922—
ReactantHCID 178509378HCID 178509378—
SolventEthanolHCID 702—
Product2-Amino-4-cyclopentylsulfanyl-6-phenyl-pyrimidine-5-carbonitrileHCID 18507396—

Reaction Steps

From 2-amino-4-phenyl-6-thioxo-1,6-dihydro-pyrimidine-5-carbonitrile, cyclopentyl bromide and sodium ethylate in ethanol. EI-MS m/e (%): 296 (M+, 36), 295 ([M—H]+, 100), 228 ([M—C5H8]+, 100).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06586441B2
Source datasetuspto-grants-2003_07
ORD IDord-9ce9f44e39fa447ab339ad4aaafb674e
Source noteuspto-grants-2003_07