Bromocyclopentane → HCID 18507396, compound

HRID 1355720Notes

Reaction equation

HRID 1355720 reaction equation
[NH2:1][C:2]1[NH:3][C:4](=[S:16])[C:5]([C:14]#[N:15])=[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[N:7]=1.[CH:17]1(Br)[CH2:21][CH2:20][CH2:19][CH2:18]1.CC[O-].[Na+]>C(O)C>[NH2:1][C:2]1[N:3]=[C:4]([S:16][CH:17]2[CH2:21][CH2:20][CH2:19][CH2:18]2)[C:5]([C:14]#[N:15])=[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[N:7]=1

Participants

5

Reactant 3

HCID 8728BromocyclopentaneHCID 2723922Sodium ethoxideHCID 178509378HCID 178509378, compound

Product 1

HCID 18507396HCID 18507396, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

From 2-amino-4-phenyl-6-thioxo-1,6-dihydro-pyrimidine-5-carbonitrile, cyclopentyl bromide and sodium ethylate in ethanol. EI-MS m/e (%): 296 (M+, 36), 295 ([M—H]+, 100), 228 ([M—C5H8]+, 100).

Sources & evidence

ORD record
ord-9ce9f44e39fa447ab339ad4aaafb674e
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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