HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexanol → 2-Amino-4-cyclohexyloxy-6-furan-2-yl-pyrimidine-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexanol | HCID 7966 | — |
| Reactant | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| Reactant | 2-Amino-4-furan-2-yl-6-methanesulfonyl-pyrimidine-5-carbonitrile | HCID 18507399 | — |
| Solvent | 1,2-Dimethoxyethane | HCID 8071 | — |
| Product | 2-Amino-4-cyclohexyloxy-6-furan-2-yl-pyrimidine-5-carbonitrile | HCID 9900466 | — |
Reaction Steps
From 2-amino-4-furan-2-yl-6-methanesulfonyl-pyrimidine-5-carbonitrile, cyclohexanol and DBU in DME. ES-MS m/e (%): 285 (M+H+, 75), 203 ([M—C6H10]+, 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06586441B2 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-aa3729070c794efe9004db3bf5989e65 |
| Source note | uspto-grants-2003_07 |