2-(Dimethylamino)ethanol → HCID 18507690, compound

HRID 1355753Notes

Reaction equation

HRID 1355753 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([C:8]2[O:9][CH:10]=[CH:11][CH:12]=2)[C:5]([C:13]#[N:14])=[C:4](S(C)(=O)=O)[N:3]=1.[CH3:19][N:20]([CH3:24])[CH2:21][CH2:22][OH:23].C1CCN2C(=NCCC2)CC1>COCCOC>[NH2:1][C:2]1[N:3]=[C:4]([O:23][CH2:22][CH2:21][N:20]([CH3:24])[CH3:19])[C:5]([C:13]#[N:14])=[C:6]([C:8]2[O:9][CH:10]=[CH:11][CH:12]=2)[N:7]=1

Participants

5

Reactant 3

HCID 79022-(Dimethylamino)ethanolHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 185073992-Amino-4-furan-2-yl-6-methanesulfonyl-pyrimidine-5-carbonitrile

Product 1

HCID 18507690HCID 18507690, compound

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

From 2-amino-4-furan-2-yl-6-methanesulfonyl-pyrimidine-5-carbonitrile, 2-dimethylaminoethanol and DBU in DME. ES-MS m/e (%): 274 (M+H+, 100).

Sources & evidence

ORD record
ord-06c98820b6374d3c8615e13d0172081c
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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