(3-Bromopropyl)benzene → HCID 18507374, compound

HRID 1355768Notes

Reaction equation

HRID 1355768 reaction equation
[NH2:1][C:2]1[NH:3][C:4](=[S:16])[C:5]([C:14]#[N:15])=[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[N:7]=1.[C:17]1([CH2:23][CH2:24][CH2:25]Br)[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1.CC[O-].[Na+]>C(O)C>[NH2:1][C:2]1[N:7]=[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[C:5]([C:14]#[N:15])=[C:4]([S:16][CH2:25][CH2:24][CH2:23][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[N:3]=1

Participants

5

Reactant 3

HCID 12503(3-Bromopropyl)benzeneHCID 2723922Sodium ethoxideHCID 178509378HCID 178509378, compound

Product 1

HCID 18507374HCID 18507374, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

From 2-amino-4-phenyl-6-thioxo-1,6-dihydro-pyrimidine-5-carbonitrile, 3-phenylpropyl bromide and sodium ethylate in ethanol. ES-MS m/e (%): 347 (M+H+, 100).

Sources & evidence

ORD record
ord-adacc3bb9a2543cdacfcb8e1f100e9e4
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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