Phenol → HCID 18507202, compound

HRID 1355773Notes

Reaction equation

HRID 1355773 reaction equation
[NH2:1][C:2]1[N:7]=[C:6](S(C)(=O)=O)[C:5]([C:12]#[N:13])=[C:4]([C:14]2[CH:19]=[C:18]([O:20][CH3:21])[C:17]([O:22][CH3:23])=[C:16]([O:24][CH3:25])[CH:15]=2)[N:3]=1.[C:26]1([OH:32])[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1.C1CCN2C(=NCCC2)CC1>COCCOC>[NH2:1][C:2]1[N:7]=[C:6]([O:32][C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[C:5]([C:12]#[N:13])=[C:4]([C:14]2[CH:19]=[C:18]([O:20][CH3:21])[C:17]([O:22][CH3:23])=[C:16]([O:24][CH3:25])[CH:15]=2)[N:3]=1

Participants

5

Reactant 3

HCID 996PhenolHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 18507557HCID 18507557, compound

Product 1

HCID 18507202HCID 18507202, compound

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

From 2-amino-4-methanesulfonyl-6-(3,4,5-trimethoxy-phenyl)-pyrimidine-5-carbonitrile, phenol and DBU in DME. ES-MS m/e (%): 379 (M+H+, 100).

Sources & evidence

ORD record
ord-db6a16bc858b4efd879ecf6ab7edd655
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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