Thiophenol → HCID 18507537, compound

HRID 1355777Notes

Reaction equation

HRID 1355777 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([S:8]([CH3:11])(=O)=O)[C:5]([C:12]#[N:13])=[C:4]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[N:3]=1.[C:20]1(S)[CH:25]=[CH:24]C=[CH:22][CH:21]=1.C1CCN2C(=NCCC2)CC1>COCCOC>[NH2:1][C:2]1[N:3]=[C:4]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:5]([C:12]#[N:13])=[C:6]([S:8][C:11]2[CH:24]=[CH:25][CH:20]=[CH:21][CH:22]=2)[N:7]=1

Participants

5

Reactant 3

HCID 7969ThiophenolHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 18507408HCID 18507408, compound

Product 1

HCID 18507537HCID 18507537, compound

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

From 2-amino-4-methanesulfonyl-6-phenyl-pyrimidine-5-carbonitrile, thiophenol and DBU in DME. EI-MS m/e (%): 304 (M+, 76), 303 ([M—H]+, 100).

Sources & evidence

ORD record
ord-6d21b4c8f0764ef58183d12b630f8fbe
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

Loading…