Thiophenol → HCID 18507473, compound

HRID 1355778Notes

Reaction equation

HRID 1355778 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([C:8]2[CH:16]=[CH:15][C:11]3[O:12][CH2:13][O:14][C:10]=3[CH:9]=2)[C:5]([C:17]#[N:18])=[C:4]([S:19]([CH3:22])(=O)=O)[N:3]=1.[C:23]1(S)[CH:28]=[CH:27]C=[CH:25][CH:24]=1.C1CCN2C(=NCCC2)CC1>COCCOC>[NH2:1][C:2]1[N:7]=[C:6]([C:8]2[CH:16]=[CH:15][C:11]3[O:12][CH2:13][O:14][C:10]=3[CH:9]=2)[C:5]([C:17]#[N:18])=[C:4]([S:19][C:22]2[CH:27]=[CH:28][CH:23]=[CH:24][CH:25]=2)[N:3]=1

Participants

5

Reactant 3

HCID 7969ThiophenolHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 18507322HCID 18507322, compound

Product 1

HCID 18507473HCID 18507473, compound

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

From 2-amino-4-benzo[1,3]dioxol-5-yl-6-methanesulfonyl-pyrimidine-5-carbonitrile, thiophenol and DBU in DME. EI-MS m/e (%): 348 (M+, 96), 347 ([M—H]+, 100).

Sources & evidence

ORD record
ord-f89d5063b9384d1989ee8e8f27a37a6a
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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