2-Methoxyethanol → HCID 18507553, compound

HRID 1355779Notes

Reaction equation

HRID 1355779 reaction equation
[NH2:1][C:2]1[N:7]=[C:6](Cl)[C:5]([C:9]#[N:10])=[C:4]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[N:3]=1.[CH3:17][O:18][CH2:19][CH2:20][OH:21].C1CCN2C(=NCCC2)CC1>COCCOC>[NH2:1][C:2]1[N:7]=[C:6]([O:21][CH2:20][CH2:19][O:18][CH3:17])[C:5]([C:9]#[N:10])=[C:4]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[N:3]=1

Participants

5

Reactant 3

HCID 80192-MethoxyethanolHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 18507370HCID 18507370, compound

Product 1

HCID 18507553HCID 18507553, compound

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

From 2-amino-4-chloro-6-phenyl-pyrimidine-5-carbonitrile, 2-methoxyethanol and DBU in DME. ES-MS m/e (%): 271 (M+H+, 100).

Sources & evidence

ORD record
ord-8a3b913c89484683a531ddfd19aa791f
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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