2-Methoxyethanol → HCID 18507659, compound

HRID 1355783Notes

Reaction equation

HRID 1355783 reaction equation
[NH2:1][C:2]1[N:7]=[C:6](S(C)(=O)=O)[C:5]([C:12]#[N:13])=[C:4]([C:14]2[CH:19]=[C:18]([O:20][CH3:21])[C:17]([O:22][CH3:23])=[C:16]([O:24][CH3:25])[CH:15]=2)[N:3]=1.[CH3:26][O:27][CH2:28][CH2:29][OH:30].C1CCN2C(=NCCC2)CC1>COCCOC>[NH2:1][C:2]1[N:7]=[C:6]([O:30][CH2:29][CH2:28][O:27][CH3:26])[C:5]([C:12]#[N:13])=[C:4]([C:14]2[CH:19]=[C:18]([O:20][CH3:21])[C:17]([O:22][CH3:23])=[C:16]([O:24][CH3:25])[CH:15]=2)[N:3]=1

Participants

5

Reactant 3

HCID 80192-MethoxyethanolHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 18507557HCID 18507557, compound

Product 1

HCID 18507659HCID 18507659, compound

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

From 2-amino-4-methanesulfonyl-6-(3,4,5-trimethoxy-phenyl)-pyrimidine-5-carbonitrile, 2-methoxyethanol and DBU in DME. EI-MS m/e (%): 360 (M+, 100), 302 (36), 287 (28), 259 (32), 43 (42).

Sources & evidence

ORD record
ord-29e03c63a288474a8a2d997b149bb9b9
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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