2-Methoxyethanol → HCID 18507470, compound

HRID 1355784Notes

Reaction equation

HRID 1355784 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([C:8]2[CH:16]=[CH:15][C:11]3[O:12][CH2:13][O:14][C:10]=3[CH:9]=2)[C:5]([C:17]#[N:18])=[C:4](S(C)(=O)=O)[N:3]=1.[CH3:23][O:24][CH2:25][CH2:26][OH:27].C1CCN2C(=NCCC2)CC1>COCCOC>[NH2:1][C:2]1[N:7]=[C:6]([C:8]2[CH:16]=[CH:15][C:11]3[O:12][CH2:13][O:14][C:10]=3[CH:9]=2)[C:5]([C:17]#[N:18])=[C:4]([O:27][CH2:26][CH2:25][O:24][CH3:23])[N:3]=1

Participants

5

Reactant 3

HCID 80192-MethoxyethanolHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 18507322HCID 18507322, compound

Product 1

HCID 18507470HCID 18507470, compound

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

From 2-amino-4-benzo [1,3]dioxol-5-yl-6-methanesulfonyl-pyrimidine-5-carbonitrile, 2-methoxyethanol and DBU in DME. EI-MS m/e (%): 314 (M+, 54), 256 ([M—MeOCH═CH2]+, 100), 214 (59).

Sources & evidence

ORD record
ord-8f2760c82ef84ba08dd0e3bdfd2df171
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

Loading…