Hydrochloric Acid → 1-(2-(2,3,4,5-Tetrahydro-7-cyano-1-benzoxepin-5-yl)ethyl)-4-(3,4-dimethoxyphenyl)piperidine
Reaction equation
[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6]2[c:7]([cH:16]1)[CH:8]([CH2:13][CH2:14][Br:15])[CH2:9][CH2:10][CH2:11][O:12]2.[CH2:18]([Al+:19][CH2:20][CH:21]([CH3:22])[CH3:23])[CH:24]([CH3:25])[CH3:26].[CH3:28][O:29][c:30]1[cH:31][c:32]([CH:38]2[CH2:39][CH2:40][NH:41][CH2:42][CH2:43]2)[cH:33][cH:34][c:35]1[O:36][CH3:37].[CH3:50][C:51]([CH2:52][CH3:53])=[O:54].[ClH:27].[H-:17].[K+:44].[K+:45].[O-:46][C:47]([O-:48])=[O:49]>>[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6]2[c:7]([cH:16]1)[CH:8]([CH2:13][CH2:14][N:41]1[CH2:40][CH2:39][CH:38]([c:32]3[cH:31][c:30]([O:29][CH3:28])[c:35]([O:36][CH3:37])[cH:34][cH:33]3)[CH2:43][CH2:42]1)[CH2:9][CH2:10][CH2:11][O:12]2Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-c37b33334c1b42c9b36ea008a20fc75c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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