Ethanethiol → HCID 18507716, compound

HRID 1355794Notes

Reaction equation

HRID 1355794 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([S:8]([CH3:11])(=O)=O)[C:5]([C:12]#[N:13])=[C:4]([C:14]2[CH:19]=[C:18]([O:20][CH3:21])[C:17]([O:22][CH3:23])=[C:16]([O:24][CH3:25])[CH:15]=2)[N:3]=1.[CH2:26](S)C.C1CCN2C(=NCCC2)CC1>COCCOC>[NH2:1][C:2]1[N:7]=[C:6]([S:8][CH2:11][CH3:26])[C:5]([C:12]#[N:13])=[C:4]([C:14]2[CH:19]=[C:18]([O:20][CH3:21])[C:17]([O:22][CH3:23])=[C:16]([O:24][CH3:25])[CH:15]=2)[N:3]=1

Participants

5

Reactant 3

HCID 6343EthanethiolHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 18507557HCID 18507557, compound

Product 1

HCID 18507716HCID 18507716, compound

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

From 2-amino-4-methanesulfonyl-6-(3,4,5-trimethoxy-phenyl)-pyrimidine-5-carbonitrile, ethyl mercaptan and DBU in DME. EI-MS m/e (%):46 (M+, 100), 315 (52).

Sources & evidence

ORD record
ord-f6312c4ee61645b1b08c158618087386
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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