2-Propanol, sodium salt (1:1) → HCID 18507222, compound

HRID 1355799Notes

Reaction equation

HRID 1355799 reaction equation
[NH2:1][C:2]1[N:7]=[C:6](SC)[C:5]([C:10]#[N:11])=[C:4]([C:12]2[CH:17]=[C:16]([O:18][CH3:19])[C:15]([O:20][CH3:21])=[C:14]([O:22][CH3:23])[CH:13]=2)[N:3]=1.[CH3:24][CH:25]([CH3:27])[O-:26].[Na+]>C(O)(C)C>[NH2:1][C:2]1[N:7]=[C:6]([O:26][CH:25]([CH3:27])[CH3:24])[C:5]([C:10]#[N:11])=[C:4]([C:12]2[CH:17]=[C:16]([O:18][CH3:19])[C:15]([O:20][CH3:21])=[C:14]([O:22][CH3:23])[CH:13]=2)[N:3]=1

Participants

4

Reactant 2

HCID 109204432-Propanol, sodium salt (1:1)HCID 18507379HCID 18507379, compound

Product 1

HCID 18507222HCID 18507222, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

From 2-amino-4-methylsulfanyl-6-(3,4,5-trimethoxy-phenyl)-pyrimidine-5-carbonitrile and sodium isopropoxide in isopropanol. ES-MS m/e (%): 367 (M+Na+, 20), 345 (M+H+, 78), 303 ([M+H—C3H6]+, 100).

Sources & evidence

ORD record
ord-10eaf64f232e495f9d5a88b95acea58a
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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