Sodium → HCID 18507228, compound

HRID 1355804Notes

Reaction equation

HRID 1355804 reaction equation
[NH2:1][C:2]1[N:7]=[C:6](SC)[C:5]([C:10]#[N:11])=[C:4]([C:12]2[CH:17]=[C:16]([O:18][CH3:19])[C:15]([O:20][CH3:21])=[C:14]([O:22][CH3:23])[CH:13]=2)[N:3]=1.[Na]>C1(O)CCCCC1>[NH2:1][C:2]1[N:7]=[C:6]([O:18][CH:16]2[CH2:17][CH2:12][CH2:13][CH2:14][CH2:15]2)[C:5]([C:10]#[N:11])=[C:4]([C:12]2[CH:17]=[C:16]([O:18][CH3:19])[C:15]([O:20][CH3:21])=[C:14]([O:22][CH3:23])[CH:13]=2)[N:3]=1

Participants

4

Reactant 2

HCID 5360545SodiumHCID 18507379HCID 18507379, compound

Product 1

HCID 18507228HCID 18507228, compound

Reagents, catalysts & solvents 1

HCID 7966CyclohexanolSolvent

Procedure

From 2-amino-4-methylsulfanyl-6-(3,4,5-trimethoxy-phenyl)-pyrimidine-5-carbonitrile and sodium cyclohexoxide in cyclohexanol. ES-MS m/e (%): 407 (M+Na+, 15), 385 (M+H+, 50), 303 ([M+H—C6H10]+, 100).

Sources & evidence

ORD record
ord-d9179d7b7ef84b43a27a8f1de779935e
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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