2-Amino-4-furan-2-yl-6-isopropenyl-pyrimidine-5-carbonitrile → HCID 18507356, compound

HRID 1355830Notes

Reaction equation

HRID 1355830 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([C:8]2[O:9][CH:10]=[CH:11][CH:12]=2)[C:5]([C:13]#[N:14])=[C:4]([C:15]([CH3:17])=[CH2:16])[N:3]=1.[H][H]>[Pd].C1COCC1>[NH2:1][C:2]1[N:7]=[C:6]([C:8]2[O:9][CH:10]=[CH:11][CH:12]=2)[C:5]([C:13]#[N:14])=[C:4]([CH:15]([CH3:17])[CH3:16])[N:3]=1

Participants

5

Reactant 2

HCID 185073502-Amino-4-furan-2-yl-6-isopropenyl-pyrimidine-5-carbonitrileHCID 178418361HCID 178418361, compound

Product 1

HCID 18507356HCID 18507356, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8028TetrahydrofuranSolvent

Procedure

From 2-amino-4-furan-2-yl-6-isopropenyl-pyrimidine-5-carbonitrile, hydrogen and palladium on charcoal in THF. ES-MS m/e (%): 229 (M+H+, 100).

Sources & evidence

ORD record
ord-50968524529747cda19a1d852875c386
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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