Chlorosuccinimide → 5-Chloro-4-furan-2-yl-6-methylsulfanyl-pyrimidin-2-ylamine

HRID 1355842Notes

Reaction equation

HRID 1355842 reaction equation
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[CH:11]=[C:10]([S:12][CH3:13])[N:9]=[C:8]([NH2:14])[N:7]=1.[Cl:15]N1C(=O)CCC1=O>C(O)(=O)C>[Cl:15][C:11]1[C:6]([C:2]2[O:1][CH:5]=[CH:4][CH:3]=2)=[N:7][C:8]([NH2:14])=[N:9][C:10]=1[S:12][CH3:13]

Participants

4

Reactant 2

HCID 31398ChlorosuccinimideHCID 185076524-Furan-2-yl-6-methylsulfanyl-pyrimidin-2-ylamine

Product 1

HCID 185074795-Chloro-4-furan-2-yl-6-methylsulfanyl-pyrimidin-2-ylamine

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

From 4-furan-2-yl-6-methylsulfanyl-pyrimidin-2-ylamine and N-chlorosuccinimide in acetic acid. ES-MS m/e (%): 244 (M{37Cl}+H+, 40), 242 (M{35Cl}+H+, 100).

Sources & evidence

ORD record
ord-372d4a58b0054ee297c165722f11534b
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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