2-(Dimethylamino)ethanol → HCID 18507433, compound

HRID 1355852Notes

Reaction equation

HRID 1355852 reaction equation
[Br:1][C:2]1[C:3]([C:12]2[O:13][CH:14]=[CH:15][CH:16]=2)=[N:4][C:5]([NH2:11])=[N:6][C:7]=1S(C)=O.[CH3:17][N:18]([CH2:20][CH2:21][OH:22])[CH3:19].C1CCN2C(=NCCC2)CC1>O1CCOCC1>[Br:1][C:2]1[C:7]([O:22][CH2:21][CH2:20][N:18]([CH3:19])[CH3:17])=[N:6][C:5]([NH2:11])=[N:4][C:3]=1[C:12]1[O:13][CH:14]=[CH:15][CH:16]=1

Participants

5

Reactant 3

HCID 79022-(Dimethylamino)ethanolHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 185072865-Bromo-4-furan-2-yl-6-methanesulfinyl-pyrimidin-2-ylamine

Product 1

HCID 18507433HCID 18507433, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

From 5-bromo-4-furan-2-yl-6-methanesulfinyl-pyrimidin-2-yl-amine, dimethylaminoethanol and DBU in dioxane. 329 (M{9Br}+H+, 95), 327 (M{10Br}+H+, 100).

Sources & evidence

ORD record
ord-6a5336596ac44d5e93dd6536822a5788
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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