2-Methoxyethylamine → HCID 18507317, compound
Reaction equation
[NH2:1][C:2]1[N:7]=[C:6](OS(C(F)(F)F)(=O)=O)[C:5]([F:16])=[C:4]([C:17]2[O:18][CH:19]=[CH:20][CH:21]=2)[N:3]=1.[CH3:22][O:23][CH2:24][CH2:25][NH2:26]>COCCOC>[F:16][C:5]1[C:6]([NH:26][CH2:25][CH2:24][O:23][CH3:22])=[N:7][C:2]([NH2:1])=[N:3][C:4]=1[C:17]1[O:18][CH:19]=[CH:20][CH:21]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
From trifluoromethanesulfonic acid 2-amino-5-fluoro-6-furan-2-yl-pyrimidin-4-yl ester and 2-methoxyethylamine in DME. ES-MS m/e (%): 253 (M+H+, 100).
Sources & evidence
- ORD record
- ord-6eb279cd6f2a40edb32eedc4e4bc93b6
- Source dataset
- uspto-grants-2003_07
- Patent number
- US06586441B2
Reaction notes
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