2-Phenylethanol → HCID 18507512, compound

HRID 1355896Notes

Reaction equation

HRID 1355896 reaction equation
[Br:1][C:2]1[C:3]([C:12]2[O:13][CH:14]=[CH:15][CH:16]=2)=[N:4][C:5]([NH2:11])=[N:6][C:7]=1S(C)=O.[CH:17]1[CH:18]=[CH:19][C:20]([CH2:23][CH2:24][OH:25])=[CH:21][CH:22]=1.C1CCN2C(=NCCC2)CC1>O1CCOCC1>[Br:1][C:2]1[C:3]([C:12]2[O:13][CH:14]=[CH:15][CH:16]=2)=[N:4][C:5]([NH2:11])=[N:6][C:7]=1[O:25][CH2:24][CH2:23][C:20]1[CH:21]=[CH:22][CH:17]=[CH:18][CH:19]=1

Participants

5

Reactant 3

HCID 60542-PhenylethanolHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 185072865-Bromo-4-furan-2-yl-6-methanesulfinyl-pyrimidin-2-ylamine

Product 1

HCID 18507512HCID 18507512, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

From 5-bromo-4-furan-2-yl-6-methanesulfinyl-pyrimidin-2-yl-amine, phenylethanol and DBU in dioxane. ES-MS m/e (%): 362 (M{81Br}+H+, 96), 360 (M{79Br}+H+, 100), 258 ([M{81Br}+H-PhCH═CH2]+, 55), 256 ([M{81Br}+H-PhCH═CH2]+, 52).

Sources & evidence

ORD record
ord-1c5d180061e04e4080890ebba23cca01
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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