6-Methyl-2-pyridylmethanol → HCID 9879609, compound

HRID 1355911Notes

Reaction equation

HRID 1355911 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([C:8]2[O:9][CH:10]=[CH:11][CH:12]=2)[C:5]([C:13]#[N:14])=[C:4](S(C)=O)[N:3]=1.[CH3:18][C:19]1[N:24]=[C:23]([CH2:25][OH:26])[CH:22]=[CH:21][CH:20]=1.C1CCN2C(=NCCC2)CC1>COCCOC>[NH2:1][C:2]1[N:7]=[C:6]([C:8]2[O:9][CH:10]=[CH:11][CH:12]=2)[C:5]([C:13]#[N:14])=[C:4]([O:26][CH2:25][C:23]2[CH:22]=[CH:21][CH:20]=[C:19]([CH3:18])[N:24]=2)[N:3]=1

Participants

5

Reactant 3

HCID 707366-Methyl-2-pyridylmethanolHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 185076922-Amino-4-(furan-2-YL)-6-(methylsulfinyl)pyrimidine-5-carbonitrile

Product 1

HCID 9879609HCID 9879609, compound

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

From 2-amino-4-furan-2-yl-6-methanesulfinyl-pyrimidine-5-carbonitrile, 6-methyl-2-pyridinemethanol and DBU in DME. ES-MS m/e (%): 330 (M+Na+, 10), 308 (M+H+, 100).

Sources & evidence

ORD record
ord-e26508fe9ea14848b9df9fb8bdc086ce
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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