HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Methyl-2-pyridylmethanol → 2-Amino-4-(5-methyl-furan-2-yl)-6-(6-methyl-pyridin-2-ylmethoxy)-pyrimidine-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Methyl-2-pyridylmethanol | HCID 70736 | — |
| Reactant | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| Reactant | 2-Amino-4-methanesulfinyl-6-(5-methyl-furan-2-yl)-pyrimidine-5-carbonitrile | HCID 18507462 | — |
| Solvent | 1,2-Dimethoxyethane | HCID 8071 | — |
| Product | 2-Amino-4-(5-methyl-furan-2-yl)-6-(6-methyl-pyridin-2-ylmethoxy)-pyrimidine-5-carbonitrile | HCID 9966886 | — |
Reaction Steps
From 2-amino-4-methanesulfinyl-6-(5-methyl-furan-2-yl)-pyrimidine-5-carbonitrile, 6-methyl-2-pyridinemethanol and DBU in DME. ES-MS m/e (%): 322 (M+H+, 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06586441B2 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-0d9dd08f9d884294a3ee55bb59946a41 |
| Source note | uspto-grants-2003_07 |