Cyclohexanol → HCID 18507713, compound

HRID 1355956Notes

Reaction equation

HRID 1355956 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([O:8]S(C(F)(F)F)(=O)=O)[C:5]([N+:16]([O-:18])=[O:17])=[C:4]([C:19]2[O:20][CH:21]=[CH:22][CH:23]=2)[N:3]=1.[CH:24]1(O)[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1.C1CCN2C(=NCCC2)CC1>COCCOC>[CH:24]1([O:8][C:6]2[C:5]([N+:16]([O-:18])=[O:17])=[C:4]([C:19]3[O:20][CH:21]=[CH:22][CH:23]=3)[N:3]=[C:2]([NH2:1])[N:7]=2)[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1

Participants

5

Reactant 3

HCID 7966CyclohexanolHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 86583748Trifluoromethanesulfonic acid 2-amino-6-furan-2-yl-5-nitro-pyrimidin-4-yl ester

Product 1

HCID 18507713HCID 18507713, compound

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

From trifluoromethanesulfonic acid 2-amino-6-furan-2-yl-5-nitro-pyrimidin-4-yl ester, cyclohexanol and DBU in DME. ES-MS m/e (%): 305 (M+H+, 100), 223 ([M+H—C6H10]+, 80).

Sources & evidence

ORD record
ord-aa4befbd108f4694bae1179e14d2e244
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

Loading…