2-Phenylethanol → HCID 9922913, compound

HRID 1355990Notes

Reaction equation

HRID 1355990 reaction equation
[Cl:1][C:2]1[C:3]([C:12]2[O:13][CH:14]=[CH:15][CH:16]=2)=[N:4][C:5]([NH2:11])=[N:6][C:7]=1S(C)=O.[CH2:17]([OH:25])[CH2:18][C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1.C1CCN2C(=NCCC2)CC1>O1CCOCC1>[Cl:1][C:2]1[C:3]([C:12]2[O:13][CH:14]=[CH:15][CH:16]=2)=[N:4][C:5]([NH2:11])=[N:6][C:7]=1[O:25][CH2:17][CH2:18][C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

Participants

5

Reactant 3

HCID 60542-PhenylethanolHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 18507343HCID 18507343, compound

Product 1

HCID 9922913HCID 9922913, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

From 5-chloro-4-furan-2-yl-6-methanesulfinyl-pyrimidin-2-yl-amine, phenethyl alcohol and DBU in dioxane. ES-MS m/e (%): 318 (M{37Cl}+H+, 33), 316 (M{35Cl}+H+, 100).

Sources & evidence

ORD record
ord-81411390cbe247fc9f848159f7a8e0d1
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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