1,8-Diazabicyclo(5.4.0)undec-7-ene → HCID 18507631, compound

HRID 1355996Notes

Reaction equation

HRID 1355996 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([C:8]2[O:9][CH:10]=[CH:11][CH:12]=2)[C:5]([C:13]#[N:14])=[C:4](S(C)=O)[N:3]=1.[NH2:18][CH2:19][C:20]1[CH:31]=[CH:30][C:23]([CH2:24][N:25]([CH2:28][CH3:29])[CH2:26][CH3:27])=[CH:22][CH:21]=1.C1CCN2C(=NCCC2)CC1>COCCOC>[NH2:1][C:2]1[N:3]=[C:4]([NH:18][CH2:19][C:20]2[CH:31]=[CH:30][C:23]([CH2:24][N:25]([CH2:28][CH3:29])[CH2:26][CH3:27])=[CH:22][CH:21]=2)[C:5]([C:13]#[N:14])=[C:6]([C:8]2[O:9][CH:10]=[CH:11][CH:12]=2)[N:7]=1

Participants

5

Reactant 3

HCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 7130831N-[4-(aminomethyl)benzyl]-N,N-diethylamineHCID 185076922-Amino-4-(furan-2-YL)-6-(methylsulfinyl)pyrimidine-5-carbonitrile

Product 1

HCID 18507631HCID 18507631, compound

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

From 2-amino-4-furan-2-yl-6-methanesulfinyl-pyrimidine-5-carbonitrile, (4-aminomethyl-benzyl)-diethyl-amine and DBU in DME. ES-MS m/e (%): 377 (M+H+, 100), 304 ([M+H-Et2NH]+, 40).

Sources & evidence

ORD record
ord-74b862ea48a54d6f82490d5c7fd11fa1
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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