1,8-Diazabicyclo(5.4.0)undec-7-ene → HCID 69782384, compound

HRID 1356007Notes

Reaction equation

HRID 1356007 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([C:8]2[O:9][CH:10]=[CH:11][CH:12]=2)[C:5]([C:13]#[N:14])=[C:4](S(C)=O)[N:3]=1.Cl.[CH2:19]([O:26][C:27](=[O:32])[NH:28][CH2:29][CH2:30][NH2:31])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1.C1CCN2C(=NCCC2)CC1>COCCOC>[CH2:19]([O:26][C:27](=[O:32])[NH:28][CH2:29][CH2:30][NH:31][C:4]1[C:5]([C:13]#[N:14])=[C:6]([C:8]2[O:9][CH:10]=[CH:11][CH:12]=2)[N:7]=[C:2]([NH2:1])[N:3]=1)[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

5

Reactant 3

HCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 12715871Benzyl N-(2-aminoethyl)carbamate hydrochlorideHCID 185076922-Amino-4-(furan-2-YL)-6-(methylsulfinyl)pyrimidine-5-carbonitrile

Product 1

HCID 69782384HCID 69782384, compound

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

From 2-amino-4-furan-2-yl-6-methanesulfinyl-pyrimidine-5-carbonitrile, (2-amino-ethyl)-carbamic acid benzyl ester hydrochloride and DBU in DME. ES-MS m/e (%): 401 (M+Na+, 20), 379 (M+H+, 100).

Sources & evidence

ORD record
ord-45a50809597c41bcbbd01b8b26230fa7
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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