1,8-Diazabicyclo(5.4.0)undec-7-ene → HCID 10224168, compound

HRID 1356024Notes

Reaction equation

HRID 1356024 reaction equation
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[C:11]([I:12])=[C:10]([S:13]([CH3:15])=O)[N:9]=[C:8]([NH2:16])[N:7]=1.SC[CH2:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][N:21]=1.C1CCN2C(=NCCC2)CC1>O1CCOCC1>[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[C:11]([I:12])=[C:10]([S:13][CH2:15][CH2:19][C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][N:21]=2)[N:9]=[C:8]([NH2:16])[N:7]=1

Participants

5

Reactant 3

HCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 1509632-PyridineethanethiolHCID 18507211HCID 18507211, compound

Product 1

HCID 10224168HCID 10224168, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

From 4-furan-2-yl-5-iodo-6-methanesulfinyl-pyrimidin-2-yl-amine, 2-mercaptoethylpyridine and DBU in dioxane. ES-MS m/e (%): 425 (M+H+, 100).

Sources & evidence

ORD record
ord-acc510630d704779a5be2a4f81789e94
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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