1,8-Diazabicyclo(5.4.0)undec-7-ene → HCID 9902160, compound

HRID 1356026Notes

Reaction equation

HRID 1356026 reaction equation
[Cl:1][C:2]1[C:3]([C:12]2[O:13][CH:14]=[CH:15][CH:16]=2)=[N:4][C:5]([NH2:11])=[N:6][C:7]=1[S:8]([CH3:10])=O.SC[CH2:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][N:21]=1.C1CCN2C(=NCCC2)CC1>O1CCOCC1>[Cl:1][C:2]1[C:3]([C:12]2[O:13][CH:14]=[CH:15][CH:16]=2)=[N:4][C:5]([NH2:11])=[N:6][C:7]=1[S:8][CH2:10][CH2:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][N:21]=1

Participants

5

Reactant 3

HCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 1509632-PyridineethanethiolHCID 18507343HCID 18507343, compound

Product 1

HCID 9902160HCID 9902160, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

From 5-chloro-4-furan-2-yl-6-methanesulfinyl-pyrimidin-2-yl-amine, 2-mercaptoethylpyridine and DBU in dioxane. ES-MS m/e (%): 335 (M{37Cl}+H+, 30), 333 (M{35Cl}+H+, 100).

Sources & evidence

ORD record
ord-2d0a87b364f7446fbed82d75d795e102
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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