Cesium carbonate → HCID 9857236, compound

HRID 1356027Notes

Reaction equation

HRID 1356027 reaction equation
[NH2:1][C:2]1[NH:7][C:6]([C:8]2[O:9][CH:10]=[CH:11][CH:12]=2)=[C:5]([C:13]#[N:14])[C:4](=[O:15])[CH:3]=1.Cl.[N:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[CH2:23]Cl.C(=O)([O-])[O-].[Cs+].[Cs+]>CN(C=O)C>[NH2:1][C:2]1[CH:3]=[C:4]([O:15][CH2:23][C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][N:17]=2)[C:5]([C:13]#[N:14])=[C:6]([C:8]2[O:9][CH:10]=[CH:11][CH:12]=2)[N:7]=1

Participants

5

Reactant 3

HCID 10796Cesium carbonateHCID 23392Picolyl chloride hydrochlorideHCID 18507515HCID 18507515, compound

Product 1

HCID 9857236HCID 9857236, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

From 6-amino-2-furan-2-yl-4-oxo-1,4-dihydro-pyridine-3-carbonitrile, 2-picolyl chloride hydrochloride and cesium carbonate in DMF. ES-MS m/e (%): 293 (M+H+, 100).

Sources & evidence

ORD record
ord-365e89ecf0c949a0a14e1fd8221ea1b8
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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