HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,8-Diazabicyclo(5.4.0)undec-7-ene → 5-Pyrimidinecarbonitrile, 2-amino-4-phenyl-6-[[2-(2-pyridinyl)ethyl]thio]-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| Reactant | 2-Pyridineethanethiol | HCID 150963 | — |
| Reactant | HCID 18507592 | HCID 18507592 | — |
| Solvent | 1,2-Dimethoxyethane | HCID 8071 | — |
| Product | 5-Pyrimidinecarbonitrile, 2-amino-4-phenyl-6-[[2-(2-pyridinyl)ethyl]thio]- | HCID 18507497 | — |
Reaction Steps
From 2-amino-4-methanesulfinyl-6-phenyl-pyrimidine-5-carbonitrile, 2-mercaptoethylpyridine and DBU in DME. ES-MS m/e (%): 334 (M+H+, 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06586441B2 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-03c5d011ab7741b3a6fc97f79e05f75b |
| Source note | uspto-grants-2003_07 |