2-(2-Hydroxyethyl)pyridine → HCID 18507704, compound

HRID 1356120Notes

Reaction equation

HRID 1356120 reaction equation
[NH2:1][C:2]1[N:7]=[C:6](S(C)=O)[C:5]([C:11]#[N:12])=[C:4]([N:13]2[CH:17]=[CH:16][CH:15]=[N:14]2)[N:3]=1.[OH:18][CH2:19][CH2:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][N:22]=1.C1CCN2C(=NCCC2)CC1>COCCOC>[NH2:1][C:2]1[N:3]=[C:4]([N:13]2[CH:17]=[CH:16][CH:15]=[N:14]2)[C:5]([C:11]#[N:12])=[C:6]([O:18][CH2:19][CH2:20][C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][N:22]=2)[N:7]=1

Participants

5

Reactant 3

HCID 76752-(2-Hydroxyethyl)pyridineHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 185075202-Amino-4-methanesulfinyl-6-pyrazol-1-yl-pyrimidine-5-carbonitrile

Product 1

HCID 18507704HCID 18507704, compound

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

From 2-amino-4-methanesulfinyl-6-pyrazol-1-yl-pyrimidine-5-carbonitrile, 2-(2-hydroxyethyl)pyridine and DBU in DME. ES-MS me/(%) 308 (M+H+, 100)

Sources & evidence

ORD record
ord-be7f7f9040b64a4db8ba8eefffcdb19b
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

Loading…