2-(2-Hydroxyethyl)pyridine → HCID 18507608, compound

HRID 1356130Notes

Reaction equation

HRID 1356130 reaction equation
[NH2:1][C:2]1[N:7]=[C:6](S(C)=O)[C:5]([C:11]#[N:12])=[C:4]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=2[O:19][CH3:20])[N:3]=1.[OH:21][CH2:22][CH2:23][C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][N:25]=1.C1CCN2C(=NCCC2)CC1>COCCOC>[NH2:1][C:2]1[N:3]=[C:4]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=2[O:19][CH3:20])[C:5]([C:11]#[N:12])=[C:6]([O:21][CH2:22][CH2:23][C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][N:25]=2)[N:7]=1

Participants

5

Reactant 3

HCID 76752-(2-Hydroxyethyl)pyridineHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 18507404HCID 18507404, compound

Product 1

HCID 18507608HCID 18507608, compound

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

From 2-amino-4-methanesulfinyl-6-(2-methoxy-phenyl)-pyrimidine-5-carbonitrile, 2-(2-hydroxyethyl)pyridine and DBU in DME. ES-MS m/e (%): 348 (M+H+, 100).

Sources & evidence

ORD record
ord-303569bf10c64dcc8ef9f0b4f3ec306c
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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