1,8-Diazabicyclo(5.4.0)undec-7-ene → HCID 69781770, compound

HRID 1356134Notes

Reaction equation

HRID 1356134 reaction equation
[NH2:1][C:2]1([C:11]2[N:16]=[CH:15][C:14]([C:17]#[N:18])=[C:13]([S:19]([CH3:21])=O)[N:12]=2)[O:10][C:6]2=[CH:7][CH:8]=[CH:9][C:5]2=[CH:4][CH2:3]1.SC[CH2:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][N:26]=1.C1CCN2C(=NCCC2)CC1>COCCOC>[NH2:1][C:2]1([C:11]2[N:16]=[CH:15][C:14]([C:17]#[N:18])=[C:13]([S:19][CH2:21][CH2:24][C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][N:26]=3)[N:12]=2)[O:10][C:6]2=[CH:7][CH:8]=[CH:9][C:5]2=[CH:4][CH2:3]1

Participants

5

Reactant 3

HCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 1509632-PyridineethanethiolHCID 69781825HCID 69781825, compound

Product 1

HCID 69781770HCID 69781770, compound

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

From 2-amino-4-benzofuran-2-yl-6-methanesulfinyl-pyrimidine-5-carbonitrile, 2-mercaptoethylpyridine and DBU in DME. ES-MS m/e (%:374 (M+H+, 100).

Sources & evidence

ORD record
ord-1fb797cc93bc4c03bdcf72501d86a70f
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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