3-Pyridinemethanol → HCID 18507554, compound

HRID 1356160Notes

Reaction equation

HRID 1356160 reaction equation
[NH2:1][C:2]1[N:7]=[C:6](S(C)=O)[C:5]([C:11]#[N:12])=[C:4]([N:13]2[CH:17]=[CH:16][CH:15]=[N:14]2)[N:3]=1.[N:18]1[CH:23]=[CH:22][CH:21]=[C:20]([CH2:24][OH:25])[CH:19]=1.C1CCN2C(=NCCC2)CC1>COCCOC>[NH2:1][C:2]1[N:3]=[C:4]([N:13]2[CH:17]=[CH:16][CH:15]=[N:14]2)[C:5]([C:11]#[N:12])=[C:6]([O:25][CH2:24][C:20]2[CH:19]=[N:18][CH:23]=[CH:22][CH:21]=2)[N:7]=1

Participants

5

Reactant 3

HCID 75103-PyridinemethanolHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 185075202-Amino-4-methanesulfinyl-6-pyrazol-1-yl-pyrimidine-5-carbonitrile

Product 1

HCID 18507554HCID 18507554, compound

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

From 2-amino-4-methanesulfinyl-6-pyrazol-1-yl-pyrimidine-5-carbonitrile, 3-pyridinemethanol and DBU in DME. EI-MS m/e (%): 293 (M+, 100), 92 (60), 65 (29), 39 (24).

Sources & evidence

ORD record
ord-d2aceaa186de470f8fc376b2cb0ebb34
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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