N-bromobutanimide → 2-Amino-4-(2-bromo-benzylamino)-6-(5-bromo-furan-2-yl)-pyrimidine-5-carbonitrile

HRID 1356176노트

반응식

HRID 1356176 반응식
[NH2:1][C:2]1[N:7]=[C:6]([NH:8][CH2:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=2[Br:16])[C:5]([C:17]#[N:18])=[C:4]([C:19]2[O:20][CH:21]=[CH:22][CH:23]=2)[N:3]=1.[Br:24]N1C(=O)CCC1=O>CN(C=O)C>[NH2:1][C:2]1[N:7]=[C:6]([NH:8][CH2:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=2[Br:16])[C:5]([C:17]#[N:18])=[C:4]([C:19]2[O:20][C:21]([Br:24])=[CH:22][CH:23]=2)[N:3]=1

참가 물질

4

반응물 2

HCID 67184N-bromobutanimideHCID 99475372-Amino-4-(2-bromo-benzylamino)-6-furan-2-yl-pyrimidine-5-carbonitrile

생성물 1

HCID 101823102-Amino-4-(2-bromo-benzylamino)-6-(5-bromo-furan-2-yl)-pyrimidine-5-carbonitrile

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

From 2-amino-4-(2-bromo-benzylamino)-6-furan-2-yl-pyrimidine-5-carbonitrile and N-bromosuccinimide in DMF. ES-MS m/e (%): 451 (M{81Br}+H+, 100), 449 (M{79Br}+H+, 95).

출처 및 근거

ORD 기록
ord-644675aed7e541319f05059eee319346
출처 데이터셋
uspto-grants-2003_07
특허 번호
US06586441B2

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