2-Chlorobenzylamine → HCID 18507255, compound

HRID 1356179Notes

Reaction equation

HRID 1356179 reaction equation
[NH2:1][C:2]1[N:7]=[C:6](S(C)=O)[C:5]([C:11]#[N:12])=[C:4]([N:13]2[CH:17]=[CH:16][CH:15]=[N:14]2)[N:3]=1.[Cl:18][C:19]1[CH:26]=[CH:25][CH:24]=[CH:23][C:20]=1[CH2:21][NH2:22].C1CCN2C(=NCCC2)CC1>COCCOC>[NH2:1][C:2]1[N:7]=[C:6]([NH:22][CH2:21][C:20]2[CH:23]=[CH:24][CH:25]=[CH:26][C:19]=2[Cl:18])[C:5]([C:11]#[N:12])=[C:4]([N:13]2[CH:17]=[CH:16][CH:15]=[N:14]2)[N:3]=1

Participants

5

Reactant 3

HCID 666482-ChlorobenzylamineHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 185075202-Amino-4-methanesulfinyl-6-pyrazol-1-yl-pyrimidine-5-carbonitrile

Product 1

HCID 18507255HCID 18507255, compound

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

From 2-amino-4-methanesulfinyl-6-pyrazol-1-yl-pyrimidine-5-carbonitrile, 2-chlorobenzylamine and DBU in DME. EI-MS m/e (%): 327 (M{37Cl}+, 10), 325 (M{35Cl}+, 35), 290 ([M—Cl]+, 100).

Sources & evidence

ORD record
ord-8975443294fd4d4d8d85f544c502d258
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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