HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorosuccinimide → 2-Amino-4-(5-chloro-furan-2-yl)-6-(3,5-dimethyl-pyridin-2-ylmethoxy)-pyrimidine-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorosuccinimide | HCID 31398 | — |
| Reactant | 2-Amino-4-(3,5-dimethyl-pyridin-2-ylmethoxy)-6-furan-2-yl-pyrimidine-5-carbonitrile | HCID 9880146 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-Amino-4-(5-chloro-furan-2-yl)-6-(3,5-dimethyl-pyridin-2-ylmethoxy)-pyrimidine-5-carbonitrile | HCID 10108896 | — |
Reaction Steps
From 2-amino-4-(3,5-dimethyl-pyridin-2-ylmethoxy)-6-furan-2-yl-pyrimidine-5-carbonitrile and N-chlorosuccinimide in DMF. ES-MS m/e (%): 358 (M{37Cl}+H+, 30), 356 (M{35Cl}+H+, 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06586441B2 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-3a40bda8dcbd440ebaaacfe50040d709 |
| Source note | uspto-grants-2003_07 |