HCID 22396943, compound → HCID 69894619, compound

HRID 1356376Notes

Reaction equation

HRID 1356376 reaction equation
Cl.Cl.ClC1C=CC(C2C3C4CCNCCC4NC=3C=CC=2)=CC=1.[Cl:24][C:25]1[CH:48]=[CH:47][CH:46]=[CH:45][C:26]=1[O:27][CH2:28][CH2:29][CH2:30][C:31]1[C:32]2[C:33]3[CH2:44][CH2:43][NH:42][CH2:41][CH2:40][C:34]=3[NH:35][C:36]=2[CH:37]=[CH:38][CH:39]=1>>[Cl:24][C:25]1[CH:48]=[CH:47][CH:46]=[CH:45][C:26]=1[O:27][CH2:28][CH2:29][CH2:30][C:31]1[C:32]2[C@@H:33]3[CH2:44][CH2:43][NH:42][CH2:41][CH2:40][C@@H:34]3[NH:35][C:36]=2[CH:37]=[CH:38][CH:39]=1

Participants

3

Reactant 2

HCID 22396943HCID 22396943, compoundHCID 22609212HCID 22609212, compound

Product 1

HCID 69894619HCID 69894619, compound

Procedure

Following the procedure for the preparation of 10-(4-chlorophenyl)-1,2,3,4,5,5a,6,10b-octahydroazepino[4,5-b]indole dihydrochloride, making non-critical variations, starting from 10-[3-(2-chlorophenoxy)propyl]-1,2,3,4, 5,6-hexahydroazepino[4,5-b]indole the title compound was prepared: 1H NMR (CDCl3) δ 1.99-2.20, 2.27, 2.78, 2.93-3.05, 3.51, 4.11, 6.48, 6.62, 6.92, 7.03, 7.19, 7.38, 7.40. HRMS (FAB) calcd for C21H25ClN2O1 (MH+) 357.1733, found 357.1749.

Sources & evidence

ORD record
ord-b8875a936ac846278bef037080a5ef88
Source dataset
uspto-grants-2003_07
Patent number
US06586421B2

Reaction notes

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