HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1356446Generated: October 26, 2026
1,1'-Biphenyl, 4-(bromomethyl)- → Methyl 6-(4-biphenylylmethoxy)nicotinate
https://huagongshe.com/reaction/1356446
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1,1'-Biphenyl, 4-(bromomethyl)- | HCID 257716 | — |
| Reactant | HCID 178498304 | HCID 178498304 | — |
| Catalyst | HCID 178418647 | HCID 178418647 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | Methyl 6-(4-biphenylylmethoxy)nicotinate | HCID 18508353 | — |
Reaction Steps
The mixture of methyl 6-hydroxynicotinate (6 g), 4-biphenylylmethyl bromide (7.7 g), silver carbonate (4.8 g), and toluene (60 ml) was stirred at 50° C. for 12 hr. The reaction mixture was further stirred at 100° C. for 6 hr and filtrated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06586475B1 |
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| Source dataset | uspto-grants-2003_07 |
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| ORD ID | ord-6e187bd992304e61ba81b759bbab9fd6 |
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| Source note | uspto-grants-2003_07 |
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