HCID 18509176, compound → HCID 18509173, compound

Participants

Reaction Steps

A mixture of 1.17 g (2.98 mmol) of the compound of Example XVI and 150 mg of Pd/C (10%) in 80 ml of EtOAc is hydrogenated under an atmosphere of hydrogen (1 atm) for 5 h. The mixture is filtered through diatomaceous earth, concentrated and purified over silica gel 60 (EtOAc/petroleum ether 1:10).

Provenance & Evidence